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The cover depicts leptin receptor expression in thymic medullary epithelial cells. Frozen thymus sections from 12-week-old mice were stained with an mTEC marker, cytokeratin 5 (green) and leptin receptor (pan marker, red). Nuclei were stained with DAPI (Blue). Final magnification 40X and areas of medulla are at a final magnification of 400X. This image occurs in the article titled 'Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution' by Gruver et al. published in this journal. The full article can be accessed at http://dx.doi.org/10.1677/JOE-09-0179. Credit: Dr A L Gruver

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