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Journal of Endocrinology (1983) 96, 23-33    DOI: 10.1677/joe.0.0960023
© 1983 Society for Endocrinology
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Ovarian follicle dynamics in mice: a comparative study of three inbred strains and an F1 hybrid

 M. J. Faddy, R. G. Gosden and R. G. Edwards

The rates of follicle growth and death have been estimated by a mathematical method in A, CBA, RIII and A x CBA strains of mice for which differential follicle counts were available. These rates were not uniform throughout life but were specific for the immature and mature phases of life. Significant heterogeneity of the rate estimates for particular follicle stages was also identified between strains and between intact and hypophysectomized mice, which explained the differing life-time patterns of follicular utilization in these animals.




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