HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by MCNATTY, K. P. Articles by BAIRD, D. T. Search for Related Content PubMed PubMed Citation Articles by MCNATTY, K. P. Articles by BAIRD, D. T.

The concentrations of FSH, oestradiol and androstenedione in the follicular fluid of normal and cystic human follicles were measured at different stages of the menstrual cycle. In addition, the number of granulosa cells in the follicles was determined.

In follicles in which FSH was detectable, the concentration of oestradiol was greater than that of androstenedione, irrespective of the stage of the cycle. In contrast, in those follicles in which FSH was undetectable and in all cystic follicles irrespective of the level of FSH, the concentration of androstenedione was greater than that of oestradiol. In follicles containing FSH there was a highly significant linear correlation between the number of granulosa cells and the concentration of follicular oestradiol (P < 0·001).

It is suggested that in human ovaries up to 90% of the oestradiol in follicular fluid may originate from the granulosa cells.

This article has been cited by other articles:

				T. Piltonen, R. Koivunen, A. Ruokonen, and J. S. Tapanainen Ovarian Age-Related Responsiveness to Human Chorionic Gonadotropin J. Clin. Endocrinol. Metab., July 1, 2003; 88(7): 3327 - 3332. [Abstract] [Full Text] [PDF]

				F. Belin, G. Goudet, G. Duchamp, and N. Gerard Intrafollicular Concentrations of Steroids and Steroidogenic Enzymes in Relation to Follicular Development in the Mare Biol Reprod, May 1, 2000; 62(5): 1335 - 1343. [Abstract] [Full Text]

				C. Mendoza, N. Cremades, E. Ruiz-Requena, F. Martinez, E. Ortega, S. Bernabeu, and J. Tesarik Relationship between fertilization results after intracytoplasmic sperm injection, and intrafollicular steroid, pituitary hormone and cytokine concentrations Hum. Reprod., March 1, 1999; 14(3): 628 - 635. [Abstract] [Full Text] [PDF]

				R. Barnes and R. L. Rosenfield The Polycystic Ovary Syndrome: Pathogenesis and Treatment Ann Intern Med, March 1, 1989; 110(5): 386 - 399. [Abstract] [PDF]