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Department of Biochemistry, Faculty of Medicine, Peradeniya Campus, Peradeniya, Sri Lanka

(Revised manuscript received 10 October 1977)

During pregnancy, the level of tri-iodothyronine (T₃) in the maternal serum is raised but this increase is not reflected in cord blood (Editorial Comment, 1973; Burke & Eastman, 1974; Walfish, 1976). To what extent the T₃ content and the composition of cord blood are interdependent or related is not clear and this study was undertaken to investigate the relationship between the levels of T₃ and immunoglobulins in cord blood.

Cord blood was collected from 53 subjects in the General Hospital, Kandy, Sri Lanka, at the time of delivery. Blood samples were allowed to clot and the serum was separated and stored at –20 °C. The concentrations of immunoglobulins G (IgG) and M (IgM) were determined by single radial immunodiffusion in agarose gels (2% for IgG; 1% for IgM) with reference to WHO standard