HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by VREEBURG, J. T. M. Search for Related Content PubMed PubMed Citation Articles by VREEBURG, J. T. M.

5-Dihydrotestosterone concentrations were found to be appreciably higher in the proximal portion of the rat epididymis than in the distal portion. Following ligation of the efferent ducts of a testis, the 5-dihydrotestosterone concentration diminished in the proximal half but not in the distal half of the epididymis. Epididymal fluid and spermatozoa were washed out from minces of epididymal tissue. The numbers of spermatozoa present in the wash fluid and in the homogenate of washed minces of epididymal tissue were used as measures for the amounts of epididymal fluid present in these fractions. Of the total amount of 5-dihydrotestosterone (30·2 ng/g tissue) in the proximal portion, 20·5 ng were localized in the epididymal fluid, whereas of the total amount of 5-dihydrotestosterone (8·6 ng/g tissue) in the distal portion, 2·8 ng were found in the epididymal fluid. The amounts of testosterone present in the fluids of both proximal and distal portions were 1–2 ng/g tissue. In contrast to the epididymal fluid, efferent duct fluid had a high concentration of testosterone (28·8 ng/ml) and a low concentration of 5-dihydrotestosterone (1·9 ng/ml). These data suggest that the fluid surrounding the spermatozoa in the testis and the epididymis contains a high concentration of androgen and that as the fluid moves from the testis to the epididymis there is a clear change in the ratio of testosterone to 5-dihydrotestosterone.

This article has been cited by other articles:

				C. A Oliveira, G. A B Mahecha, K. Carnes, G. S Prins, P. T K Saunders, L. R Franca, and R. A Hess Differential hormonal regulation of estrogen receptors ER{alpha} and ER{beta} and androgen receptor expression in rat efferent ductules Reproduction, July 1, 2004; 128(1): 73 - 86. [Abstract] [Full Text] [PDF]

				A. M. Silva, D. B.C. Queiroz, E. F. Castro Neto, M. d. G. Naffah-Mazzacoratti, R. O. Godinho, C. S. Porto, G. Gutierrez-Ospina, and M. C. W. Avellar Segment-Specific Decrease of Both Catecholamine Concentration and Acetylcholinesterase Activity Are Accompanied by Nerve Refinement in the Rat Cauda Epididymis During Sexual Maturation J Androl, May 1, 2002; 23(3): 374 - 383. [Abstract] [Full Text] [PDF]

				G. P. H. Leung, S. B. Cheng-Chew, and P. Y. D. Wong Nongenomic effect of testosterone on chloride secretion in cultured rat efferent duct epithelia Am J Physiol Cell Physiol, May 1, 2001; 280(5): C1160 - C1167. [Abstract] [Full Text] [PDF]