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Journal of Endocrinology (1949) 6, 197-204       DOI: 10.1677/joe.0.0060197
© 1949 Society for Endocrinology
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ADRENALECTOMY IN THE GOAT AND ITS EFFECTS ON THE CHEMICAL CONSTITUENTS OF THE BLOOD

A. T. COWIE and JAMES STEWART

The effects of adrenalectomy have been studied mainly in the rat, dog and cat, and to a lesser extent in the guinea-pig and rabbit. Scant attention, however, has been given to the study of the effects of adrenalectomy in the smaller ruminants. In 1901, Moore & Purinton investigated the survival period after adrenalectomy in two adult female goats and two kids. The kids were unilaterally adrenalectomized a few hours after birth, and the second adrenal removed 34–35 days later. Both died 49–66 hr. after completion of adrenalectomy. One of the adult goats died 8 days after removal of the second adrenal, the other remained normal and was killed 22 days after the operation. No gross adrenal tissue was found at autopsy. In sheep, the effects of adrenalectomy have been studied by Strand, Anderson & Allcroft [1934]. Five animals were successfully adrenalectomized and survived 34–60 hr. after removal of the second







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