HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by SIMPSON, S. A. Articles by WILLIAMS, P. C. Search for Related Content PubMed PubMed Citation Articles by SIMPSON, S. A. Articles by WILLIAMS, P. C.

Normal mating behaviour may be induced in spayed rats by successive injections of oestrogen and progesterone, but the response to oestrogen alone is reported to be variable or of low intensity. (The subject was reviewed by Young in 1941.)

In connexion with some other work we wished to establish the dose of oestrogen needed to induce mating in our rats. We also investigated Ring's suggestion [1945] that heat induced by oestrogen is only a special case of the co-operation of oestrogen and progesterone in that the injected oestrogen stimulates the secretion of progesterone (or of some other steroid with like action) by the adrenals. Our results contradicted this suggestion, which had only been supported by negative evidence.

MATERIAL AND METHOD: Young, virgin rats of an albino Wistar strain were spayed or spayed and adrenalectomized when they weighed 100–120 g. If adrenalectomized they were given 1 % sodium chloride to drink and