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In order to study the rate of growth of organs under endocrine control and to determine the time of onset or cessation of growth-promoting endocrine influences, it is usually necessary to relate the rate of growth of the organ in question to that of the body as a whole.

Relative growth analysis, as developed by Huxley [1924], can easily be applied to teat growth as has been done by Bottomley & Folley [1938] for the guinea-pig and Folley, Scott Watson & Bottomley [1941] for the goat, since teat length is an easily measured quantity. In the case of the mammary gland, however, the only suitable quantitative criterion is the mammary-gland area and this can be used only with animals such as the mouse, rat or monkey in which the mammae consist of relatively flat sheets of tissue.

The first attempt to correlate mammary growth with the growth rate of some