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Antiserum to ovine luteinizing hormone (LH) interrupted pregnancy when administered to mice either on days 1 to 3 or on any single day from days 2 to 7 after mating (Munshi & Rao, 1967; Munshi, Purandare & Rao, 1972). Progesterone alone could overcome these inhibitory effects, suggesting interference with the function of the corpus luteum (Munshi et al. 1972).

Finn & Martin (1967) observed that in mice on the 3rd day of pregnancy, large numbers of the epithelial cells of the uterine lumen and glands but very few of the stromal cells are undergoing mitoses, whereas on the 4th day the situation is reversed. This change in the pattern of cell division is due to the secretion of progesterone (Martin & Finn, 1968; Finn & Martin, 1969), a factor considered important in the preparation of the uterus for implantation (Finn, Martin & Carter, 1969). It was of interest to us