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Human chorionic somato-mammotrophin (HCS) and the activities of heat-stable alkaline phosphatase (HSAP) and cysteine aminopeptidase (CAP) in the serum of normal pregnant women were studied. The hormone and enzymes were detectable at the early stage of pregnancy and all showed an increase with the progress of gestation. A highly significant correlation was found between HCS and activities of HSAP and CAP during all stages of gestation.

Human chorionic somato-mammotrophin and oestrogens were measured in the urine of pregnant women. The correlation coefficient between these factors was smaller than that found between serum enzymes and HCS but was still significant.

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				B. Musicki, G. J. Pepe, and E. D. Albrecht Functional Differentiation of Placental Syncytiotrophoblasts during Baboon Pregnancy: Developmental Expression of Chorionic Somatomammotropin Messenger Ribonucleic Acid and Protein Levels J. Clin. Endocrinol. Metab., December 1, 1997; 82(12): 4105 - 4110. [Abstract] [Full Text] [PDF]