HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by JOHNSTON, C. I. Search for Related Content PubMed Articles by JOHNSTON, C. I.

Antibodies to [8-lysine]-vasopressin (LVP) were produced in rabbits by a macrophage harvesting technique. Using these antibodies a radioimmunoassay for vasopressin was established using LVP as standard and for labelling with ¹²⁵I. The antibody demonstrated complete cross-reactivity to [8-arginine]- and [8-ornithine]-vasopressin but concentrations of oxytocin 1000 times greater caused no displacement. A simple extraction procedure for antidiuretic hormone (ADH) in plasma is described. Employing this extraction procedure followed by radioimmunoassay, plasma levels of ADH were measured in sheep. The mean level of plasma ADH in nine sheep was found to be 5·28 ± 1·18 in arterial blood and this rose to 21·04 ± 7·29 µu./ml after haemorrhage of 10 to 20% of their blood volume.