HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by BAUMAN, J. W. Search for Related Content PubMed Articles by BAUMAN, J. W., Jr.

Glomerular filtration rate (GFR), renal plasma flow (RPF) and solute-free water reabsorption (T^cH₂O) were measured in anaesthetized intact and hypophysectomized rats and in hypophysectomized rats treated with corticotrophin (ACTH). GFR and RPF were measured by [¹⁴C]inulin and [³H]p-aminohippuric acid clearances. In agreement with previous reports, these two functions were found to be reduced by hypophysectomy. Infusion of vasopressin increased T^cH₂O in the intact rat but failed to produce a significant change in the hypophysectomized rat. Treatment of hypophysectomized rats with ACTH restored the effects of vasopressin on T^cH₂O. ACTH also increased the RPF of hypophysectomized rats to normal values, but only partially restored GFR.