HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by DASH, J. A. Articles by LINDSAY, D. B. Search for Related Content PubMed Articles by DASH, J. A. Articles by LINDSAY, D. B.

Insulin concentrations were determined in sheep plasma using a radio-immunoassay and a bioassay (rat epididymal fat pad) technique. Both methods indicate an increase in plasma insulin after intravenous injection of insulin or glucose into sheep, followed by a decline as glucose levels return to normal. With both methods, plasma levels before injection are comparable with values reported for human plasma. However, the response of the fat pad to sheep plasma was fully inhibited by anti-insulin serum; acid ethanol extraction did not increase the apparent level of insulin; the concentrations indicated by the fat-pad method correspond with values that have been obtained with the diaphragm assay. No evidence has been found for a bound form of insulin in sheep plasma. There was no potentiation by sheep plasma of the response of the fat pad to crystalline insulin.