HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Web of Science (4) Citing Articles via Google Scholar Google Scholar Articles by BOYLE, J. A. Articles by DALAKOS, T. G. Search for Related Content PubMed PubMed Citation Articles by BOYLE, J. A. Articles by DALAKOS, T. G.

The association of endemic goitre with 'hard water' has been recognized for many years (see Murray, Ryle, Simpson & Wilson, 1948). Since radioactive iodine is such a useful tool in the investigation of thyroid physiology it is surprising that the effects of calcium on the function of the normal thyroid gland in man have not been studied with isotopic techniques. Studies of thyroid function with ¹³²I on volunteers with dietary calcium supplements during 6 weeks are therefore reported.

Six euthyroid subjects without a goitre were investigated. Five received 1·9 g. calcium daily in five divided doses as effervescent Calcium Sandoz tablets dissolved in 100 ml. tap water. Each tablet contains 4 g. calcium gluconate (equivalent to 0·38 g. calcium) and 20 mg. ascorbic acid. The sixth subject received placebo tablets which did not contain calcium.

The thyroidal uptake of radioactive iodine 2 hr. after an oral dose of 25