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and N. KOVAI

Hayashida & Li (1958) and Hayashida (1962) reported that ox growth hormone produced antibodies against ox lactogenic hormone, a serum protein and the growth hormone itself, but Chadwick, Folley & Gemzell (1961) obtained negative results with ox growth hormone in the bioassay for lactogenic hormone. Ferguson & Wallace (1963) found that the electrophoretic bands characteristic of prolactin could be detected on starch-gel electrophoretograms of some ox growth hormone preparations.

The purpose of this communication is to show the results of assays of various ox growth hormone preparations for the presence of prolactin, as measured by the deciduoma method (Kovai, 1963). In this method the formation of deciduomata in the damaged uterine horn of adult hypophysectomized mice is used as the endpoint. In the mouse, prolactin has luteotrophic properties; it is believed that luteal cells secrete progesterone, which causes decidual reactions.

The results of assays for prolactin on two preparations (72-GH-1