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It has been generally considered that copious secretion of milk begins only after parturition. Many biochemical studies on the synthetic activity of the mammary gland of pregnant animals seem to support this conception (Folley, 1956, 1961; Folley & French, 1949; Kuretani, 1957; Shimizu, Shoda, Kuretani & Ugami, 1957). Histological studies on the mammary gland tissue of the rat, however, indicate the presence of secretory products in alveoli in late stages of pregnancy (Curtiss, 1949; Jeffers, 1935), although no evidence has been provided that these are identical with milk.

The present study was performed to discover the time of initiation of milk secretion in pregnant rats, the appearance of lactose in the mammary gland tissue being used as an indicator of lactogenesis, since lactose is one of the components of milk.

Virgin female rats of the Wistar strain, weighing 145—180 g., were placed with males. Vaginal smears were taken every morning

This article has been cited by other articles:

				L. L. Roth and J. S. Rosenblatt Mammary Glands of Pregnant Rats: Development Stimulated by Licking Science, March 18, 1966; 151(3716): 1403 - 1404. [Abstract] [PDF]