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APART from the work of Cole and his collaborators, little is known about the rate of production and the maximal concentration of the gonadotrophin in the serum of pregnant mares. Cole & Hart [1930] showed that the hormone first appears in the blood between the 5th and 6th week and that maximal concentration is attained between the 60th and the 90th day. In a later paper Cole [1938] observed that the peak concentration of gonadotrophin in the serum of pregnant ponies was four times as great as it was in the blood of mares of larger breeds, and also that it occurred for an even shorter time. The importance of accurate information about the time and duration of peak concentration has led us to obtain data for breeds of ponies available in England.

We have also investigated the extent to which the pregnant mare can be bled on one occasion,

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				A. S. Parkes SOME ASPECTS OF THE ENDOCRINE ENVIRONMENT OF THE FETUS Cold Spring Harb Symp Quant Biol, January 1, 1954; 19(0): 3 - 8. [Abstract] [PDF]