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This Article Full Text Full Text (PDF) All Versions of this Article: JOE-08-0161v1 198/3/439    most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Google Scholar Articles by King, P. J Articles by Laufer, E. PubMed PubMed Citation Articles by King, P. J Articles by Laufer, E.

Barts and the London School of Medicine, Centre for Endocrinology, London EC1M 6BQ, UK¹ Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York 10032, USA

(Correspondence should be addressed to P J King; Email: p.j.king{at}qmul.ac.uk)

The hedgehog (Hh) pathway is an evolutionarily conserved signalling pathway that is required for many essential tissue and cellular properties such as patterning fields of cells or regulating cell differentiation and proliferation. Disruption of the pathway results in serious pathologies. In this review, we provide an update on recent findings in the field of vertebrate Hh signalling and also describe contributions of Hh signalling to the development, maintenance and pathology of endocrine tissues.